蒙阴长毛兔传染性水泡性口炎是由水泡性口炎病毒引起的蒙阴长毛兔急性传染病，主要特点是口腔粘膜出现水疱性炎症。由于伴有大量流涎，故又称“流涎病”。病毒主要存在于病蒙阴长毛兔的疱液、疱皮及局部淋巴结中。

　　Infectious vesicular stomatitis in Mongolian long haired rabbits is an acute infectious disease caused by vesicular stomatitis virus, characterized by vesicular inflammation of the oral mucosa. Due to excessive salivation, it is also known as "salivation disease". The virus mainly exists in the blister fluid, blister skin, and local lymph nodes of the Mongolian long haired rabbit.

　　【诊断要点】

　　【 Diagnostic Key Points 】

　　(一)流行特征。病蒙阴长毛兔是主要传染源。通过消化道感染，发病率可达60%以上，死亡率可达50%左右。主要影响1-3月龄的蒙阴长毛兔子。尤其是断奶后1-2周龄的幼蒙阴长毛兔。这种情况在成年蒙阴长毛兔子中较少发生。喂养不当。饲喂发霉带刺的饲料、口腔损伤等均可诱发本病。其多发于春、秋两季。

　　（1） Popular features. The Mengyin long haired rabbit is the main source of infection. Through digestive tract infection, the incidence rate can reach more than 60%, and the mortality can reach about 50%. Mainly affecting Mongolian long haired rabbits aged 1-3 months. Especially for young Mongolian long haired rabbits aged 1-2 weeks after weaning. This situation is less common in adult shaded long haired rabbits. Improper feeding. Feeding moldy and prickly feed, oral damage, etc. can all induce this disease. It is more common in spring and autumn.

　　(2)症状：潜伏期3-4天。发病初期，口腔粘膜出现潮红、充血。随后，唇、舌、硬腭、口腔粘膜出现小米扁豆大小的水泡；它们充满了透明的纤维素液体。很快水癌破裂，常引起继发细菌感染，引起唇、舌和口腔粘膜坏死，形成斑块和溃疡，并伴有恶臭。同时，还有大量的流涎，使得脖子、胸部和前爪上的毛发都湿漉漉的。局部皮肤经常被浸泡和刺激，引起炎症和脱发。外生殖器也可能出现溃疡性病变。由于蒙阴长毛兔子不断流涎，大量流失水分、粘液蛋白和某些代谢产物，会出现一些全身症状。由于口腔病变，食欲不振、疲惫不堪、消化不良、腹泻等，病蒙阴长毛兔体温升高4041，精神抑郁、失重、虚弱。病程一般为2-10天，因劳累而死亡。

　　(2) Symptoms: Incubation period of 3-4 days. In the early stages of the disease, the oral mucosa appears flushed and congested. Subsequently, blisters ranging from millet to bean sized appeared on the lips, tongue, hard palate, and oral mucosa; They are filled with transparent cellulose liquid. Quickly, water cancer ruptures, often causing secondary bacterial infections that lead to necrosis of the lips, tongue, and oral mucosa, forming plaques and ulcers, accompanied by a foul odor. At the same time, there was also a lot of drooling, making the hair on the neck, chest, and front paws wet. Local skin is often soaked and irritated, causing inflammation and hair loss. Ulcerative lesions may also occur in the external genitalia. Due to the continuous drooling of Mongolian long haired rabbits, a large amount of water, mucous proteins, and certain metabolites are lost, resulting in some systemic symptoms. Due to oral lesions, loss of appetite, fatigue, indigestion, diarrhea, etc., the body temperature of the Mengyin Long haired Rabbit has risen to 4041, with mental depression, weight loss, and weakness. The course of the disease usually lasts for 2-10 days, and eventually leads to death due to fatigue.

　　(3)病变。尸检显示口腔粘膜、舌和唇粘膜出现水泡、糜烂和溃疡。咽、喉部积有泡沫状唾液，唾液腺红肿。胃膨胀并充满粘稠液体。肠粘膜有卡他性炎症改变。身体非常消瘦。

　　(3) Disease. Autopsy showed blisters, erosions, and ulcers on the oral mucosa, tongue, and lip mucosa. There is foam like saliva in the pharynx and throat, and the salivary glands are red and swollen. The stomach swells and is filled with viscous liquid. There is catarrhal inflammation in the intestinal mucosa. The body is very thin.

　　[防治技术]

　　[Prevention and Control Technology]

　　(一)预防。应加强饲养管理，防止病蒙阴长毛兔传入。应给蒙阴长毛兔喂松软易消化的草料，防止口腔外伤。如果发现病蒙阴长毛兔，应立即隔离，并更换、柔软、易消化的草料。蒙阴长毛兔笼、蒙阴长毛兔舍及用具应用2%烧碱溶液、20%热草木灰水或0.5%过氧乙酸。

　　（1） Prevention. We should strengthen the management of animal husbandry to prevent the transmission of disease prone long haired rabbits. Soft and easily digestible grass should be fed to Mongolian long haired rabbits to prevent oral trauma. If a sick Mongolian long haired rabbit is found, it should be immediately isolated and replaced with high-quality, soft, and easily digestible grass. The Mongolian long haired rabbit cage, Mongolian long haired rabbit house and utensils should be disinfected with 2% caustic soda solution, 20% hot grass ash water or 0.5% peracetic acid.

　　(2)。病蒙阴长毛兔给予磺胺二甲嗪0.1g/kg体重口服，每日1次，连续数日，并以苏打水为饮水，以控制继发细菌感染，减轻口腔炎症。同时进行对症。用0.1%高锰酸钾、1%盐水、2%硼酸溶液（或明矾水）冲洗口腔。涂上碘甘油或撒上青黛粉，用金银花或野菊花水煎喂。

　　(2) Treatment. Sick Mongolian long haired rabbits were given 0.1g/kg body weight of sulfamethoxazole orally once a day for several consecutive days, with soda water as drinking water, to control secondary bacterial infections and reduce oral inflammation. Simultaneously provide symptomatic treatment. Rinse the oral cavity with 0.1% potassium permanganate, 1% saline solution, and 2% boric acid solution (or alum water). Coat with iodine glycerin or sprinkle with indigo powder, fry with honeysuckle or wild chrysanthemum water and feed.

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